What is SM?
Suspecting SM
- Differential diagnosis
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Diagnosing SM
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Systemic mastocytosis (SM) is a rare and typically debilitating mast cell disease^1,2

Driven by KIT D816V in ~95% of cases^3,4

What is SM?

Recognising the common symptoms of SM is the key to earlier identification

Symptoms of SM

Explore how to differentiate SM from more common conditions

Differential diagnosis

Access practical guidance on initial testing when SM is suspected

Screening before referral

Order a complete workup to confirm a diagnosis of SM

Screening after referral

Support your patients following diagnosis by monitoring symptom burden and disease progression

Monitoring

Resource Library

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References V

Gülen T, et al. J Intern Med. 2016;279(3):211–228.
Mesa RA, et al. Cancer. 2022;128(20):3700–3708.
Ungerstedt J, et al. Cancers (Basel). 2022;14(16):3942.
Kristensen T, et al. J Mol Diagn. 2011;13(2):180–188.
Ustun C, et al. Blood Adv. 2023;9(9):2048–2062.

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Systemic mastocytosis (SM) is a rare and typically debilitating mast cell disease1,2

Resource Library

Access practical tools and SM resources – all in one place

Stay up to date

References V

Systemic mastocytosis (SM) is a rare and typically debilitating mast cell disease^1,2